Apoptosis and free radicals

被引:66
作者
Stoian, I [1 ]
Oros, A [1 ]
Moldoveanu, E [1 ]
机构
[1] VICTOR BABES INST, R-76201 BUCHAREST, ROMANIA
关键词
NF-KAPPA-B; SUPEROXIDE-DISMUTASE; OXIDATIVE STRESS; NITRIC-OXIDE; CELL-DEATH; ACTIVATION; ACETYLCYSTEINE; INHIBITION; MECHANISMS; INDUCTION;
D O I
10.1006/bmme.1996.0072
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Free radicals that appear during physiological processes may lead to apoptosis in some pathological conditions when antioxidant capacity of the tissue is surpassed. Additionally, free radicals are involved in the control of apoptosis; antioxidant agents suppress apoptosis induced by a variety of stimuli. The possibility that apoptosis is regulated by modulation of the levels of free radicals is discussed. (C) 1996 Academic Press, Inc.
引用
收藏
页码:93 / 97
页数:5
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