The molecular biology of SRY and its role in sex determination in mammals

被引：26

作者：

Koopman, P

机构：

[1] Centre for Molecular and Cellular Biology, The University of Queensland, Brisbane, QLD

来源：

REPRODUCTION FERTILITY AND DEVELOPMENT | 1995年 / 7卷 / 04期

关键词：

D O I：

10.1071/RD9950713

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

SRY is the gene that initiates the genetic cascade leading to testis development in mammals. Since its discovery in 1990 and the direct demonstration of its male-determining role in transgenic mice, attention has turned to understanding the biochemical mode of action of the SRY gene product, and to the identification of other genes in the sex-determining pathway. Recent progress in these efforts is summarized in this review.

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页码：713 / 722

页数：10

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