The Pfam protein families database

被引:1366
作者
Finn, Robert D. [1 ]
Tate, John [1 ]
Mistry, Jaina [1 ]
Coggill, Penny C. [1 ]
Sammut, Stephen John [1 ]
Hotz, Hans-Rudolf [1 ]
Ceric, Goran [2 ]
Forslund, Kristoffer [3 ]
Eddy, Sean R. [2 ]
Sonnhammer, Erik L. L. [3 ]
Bateman, Alex [1 ]
机构
[1] Wellcome Trust Sanger Inst, Hinxton, Cambs, England
[2] Howard Hughes Med Inst, Ashburn, VA 20147 USA
[3] Stockholm Univ, Stockholm Bioinformat Ctr, Albanova, SE-10691 Stockholm, Sweden
基金
英国医学研究理事会; 英国生物技术与生命科学研究理事会;
关键词
D O I
10.1093/nar/gkm960
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam ( 22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI GenPept and on sequences from selected metage-nomics projects. Pfam is available on the web from the consortium members using a new, consistent and improved website design in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/), as well as from mirror sites in France (http://pfam.jouy.inra.fr/) and South Korea (http://pfam.ccbb.re.kr/).
引用
收藏
页码:D281 / D288
页数:8
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