Reconsidering Neuroprotection in the Reperfusion Era

被引:140
作者
Savitz, Sean I. [1 ,2 ]
Baron, Jean-Claude [3 ]
Yenari, Midori A. [4 ,5 ]
Sanossian, Nerses [6 ,7 ]
Fisher, Marc [8 ]
机构
[1] UTHealth, Inst Stroke & Cerebrovasc Dis, Houston, TX USA
[2] UTHealth, Dept Neurol, Houston, TX USA
[3] Univ Paris 05, INSERM, Hop St Anne, Dept Neurol,U894, Paris, France
[4] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
[5] San Francisco VA Med Ctr, Dept Neurol, San Francisco, CA USA
[6] Roxanna Todd Hodges Comprehens Stroke Clin, Los Angeles, CA USA
[7] Univ Southern Calif, Dept Neurol, Los Angeles, CA USA
[8] Beth Israel Deaconess Med Ctr, Dept Neurol, Boston, MA 02215 USA
关键词
neuroprotection; reperfusion; reperfusion injury; secondary prevention; thrombectomy; ACUTE ISCHEMIC-STROKE; DIRECT-CURRENT STIMULATION; NORMOBARIC OXYGEN-THERAPY; PLASMINOGEN-ACTIVATOR; THROMBOLYTIC THERAPY; OXIDATIVE STRESS; FOCAL ISCHEMIA; BRAIN-DAMAGE; TIME WINDOW; INJURY;
D O I
10.1161/STROKEAHA.117.017283
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:3413 / 3419
页数:7
相关论文
共 44 条
[31]   A systematic review of stroke recognition instruments in hospital and prehospital settings [J].
Rudd, Matthew ;
Buck, Deborah ;
Ford, Gary A. ;
Price, Christopher I. .
EMERGENCY MEDICINE JOURNAL, 2016, 33 (11) :818-822
[32]   Prehospital Use of Magnesium Sulfate as Neuroprotection in Acute Stroke [J].
Saver, Jeffrey L. ;
Starkman, Sidney ;
Eckstein, Marc ;
Stratton, Samuel J. ;
Pratt, Franklin D. ;
Hamilton, Scott ;
Conwit, Robin ;
Liebeskind, David S. ;
Sung, Gene ;
Kramer, Ian ;
Moreau, Gary ;
Goldweber, Robert ;
Sanossian, Nerses .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (06) :528-536
[33]   Future of neuroprotection for acute stroke: In the aftermath of the SAINT trials [J].
Savitz, Sean I. ;
Fisher, Marc .
ANNALS OF NEUROLOGY, 2007, 61 (05) :396-402
[34]   Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target [J].
Shuaib, Ashfaq ;
Butcher, Ken ;
Mohammad, Askar A. ;
Saqqur, Maher ;
Liebeskind, David S. .
LANCET NEUROLOGY, 2011, 10 (10) :909-921
[35]   A pilot study of normobaric oxygen therapy in acute ischemic stroke [J].
Singhal, AB ;
Benner, T ;
Roccatagliata, L ;
Koroshetz, WJ ;
Schaefer, PW ;
Lo, EH ;
Buonanno, FS ;
Gonzalez, RG ;
Sorensen, AG .
STROKE, 2005, 36 (04) :797-802
[36]   Normobaric hyperoxia reduces MRI diffusion abnormalities and infarct size in experimental stroke [J].
Singhal, AB ;
Dijkhuizen, RM ;
Rosen, BR ;
Lo, EH .
NEUROLOGY, 2002, 58 (06) :945-952
[37]   Glucose and NADPH Oxidase Drive Neuronal Superoxide Formation in Stroke [J].
Suh, Sang Won ;
Shin, Byung Seop ;
Ma, Hualong ;
Van Hoecke, Michael ;
Brennan, Angela M. ;
Yenari, Midori A. ;
Swanson, Raymond A. .
ANNALS OF NEUROLOGY, 2008, 64 (06) :654-663
[38]   The inflammatory response in stroke [J].
Wang, Qing ;
Tang, Xian Nan ;
Yenari, Midori A. .
JOURNAL OF NEUROIMMUNOLOGY, 2007, 184 (1-2) :53-68
[39]   Activated Protein C Analog Protects From Ischemic Stroke and Extends the Therapeutic Window of Tissue-Type Plasminogen Activator in Aged Female Mice and Hypertensive Rats [J].
Wang, Yaoming ;
Zhao, Zhen ;
Chow, Nienwen ;
Rajput, Padmesh S. ;
Griffin, John H. ;
Lyden, Patrick D. ;
Zlokovic, Berislav V. .
STROKE, 2013, 44 (12) :3529-3536
[40]   Evidence of reperfusion injury, exacerbated by thrombolytic therapy, in human focal brain ischemia using a novel imaging marker of early blood-brain barrier disruption [J].
Warach, S ;
Latour, LL .
STROKE, 2004, 35 (11) :2659-2661