脑微出血与脑卒中

被引:24
作者
桂雅星 [1 ]
黄鉴政 [2 ]
机构
[1] 浙江大学附属第二医院干部科
[2] 浙江大学附属第二医院神经内科
关键词
脑微出血; 梯度回波磁共振; 卒中;
D O I
暂无
中图分类号
R743 [脑血管疾病];
学科分类号
1002 ;
摘要
目的探讨脑微出血与脑卒中发生、发展的联系。方法卒中患者83例,分为脑缺血组(43例)和脑出血组(40例),以同期住院的50岁以上非脑卒中患者设立对照组(32例)。采用T2加权梯度回波MRI观察各病例脑微出血、卒中病灶、腔隙性梗塞以及白质疏松情况,同时记录卒中患者的高血压、糖尿病、高脂血症、卒中病史以及阿司匹林使用史。结果微出血在缺血组和出血组的发生率分别为34.9%、75.0%,对照组9.4%。各组微出血均最常见于基底节区。微出血与高血压、卒中病史相关(P<0.01),与高脂血症、糖尿病病史及使用阿司匹林无关(P>0.05)。微出血的严重程度与腔隙性梗塞、白质疏松的严重程度相关(P<0.01)。微出血在卒中病灶区域同侧或对侧分布无显著性差异(P>0.05)。出血组微出血在卒中病灶区域的分布率明显高于缺血组。结论微出血与脑卒中,特别是与出血性脑卒中有密切关系,对卒中患者出血性转化具有预测意义。
引用
收藏
页码:1245 / 1248
页数:4
相关论文
共 11 条
[1]  
O ld m icrobleedsare a potentialrisk factorforcerebralbleeding afterischem ic stroke:a gradient-echo T2*-w eighted brain M RIstudy. Nighoghossian N,H erm ierM,A deleineP,etal. Stroke . 2002
[2]   Neurology [C]. 
The 5th International Congress of Pathophysiology
,2006
[3]  
Cerebralm icrobleeds as a risk factorforsubsequentintracerebralhem orrhagesam ong patientsw ith acuteischem icstroke. Fan Y H,Zhang L,Lam W W,etal. Stroke . 2003
[4]  
M agnetic resonance im aging detection ofm icrobleedsbefore throm bolysis:an em erging application. Kidw ellCS,SaverJL,V illablanca JP,etal. Stroke . 2002
[5]  
A ssociation ofsm all,dense low density lipoprotein w ith stroke. Liu X N,G ao Y,Y e J,etal. Zhonghua YiX ue Za Zhi . 2003
[6]  
A new rating scalefor age-related white m atter changes applicable to M RI and CT. W ahlund LO,BarkhofF,FazekasF,etal. Stroke . 2001
[7]  
G radientecho m agnetic resonance im aging in theprediction ofhem orrhagicvsischem icstroke:a need forthe consideration ofthe extentofleukoariosis. Kim D E,Bae H J,Lee SH,etal. A rch N eurol . 2002
[8]  
Com parative analysis ofthe spatial distribution and severity ofcerebralm icrobleedsand old lacunes. Lee SH,Bae H J,K o SB,etal. J N eurolN eurosurg Psychiatry . 2004
[9]  
D otlikehem osiderin spots on T2*-w eighted m agnetic resonance im aging as a predictor of strokerecurrence:a prospective study. Im aizum iT,H oritaY,H ashim oto Y,etal. JN eurosurg . 2004
[10]  
D otlike hem osiderin spotsare associated w ith past hem orrhagic strokes in patients w ith lacunar infarcts. Im aizum iT,H onm aT,H oritaY,etal. JN euroim aging . 2005