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Neurology
被引：0
作者：
机构：
关键词：
Neurology;
会议名称：
The 5th International Congress of Pathophysiology
会议时间：
2006-06-01
会议地点：
中国北京
中图分类号：
R741 [神经病学]
学科分类号：
1002
类型：
摘要：
<正>MicroRNA in neural stem cell development Yue Feng, Anthony Lau, Jian Han, Qun - ying Yang, Chiung - mei Lu (Department of Pharmacology, Emory University, 5029 Rollins Research Center, 1510 Clifton Road, Atlanta 30322, USA; Genaco Biomedical Products, yfeng@ emory. edu) MicroRNAs (miRNAs) are an evolutionarily conserved novel class of small non -coding RNAs, which functions in gene silencing by repressing protein synthesis from their mRNA target that harbor incomplete sequence complementarity. More than 300 miRNAs are encoded by the human genome. The expression levels of many miRNAs are vigorously regulated during normal development in a variety of tissue types especially during stem cell differentiation. Moreover, an increasing numbers of examples have been reported demonstra-
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页码：131 / 147
页数：17