DECREASED SENSITIVITY OF AN INTERFERON-RESISTANT SUBLINE OF MURINE LEUKEMIA L-1210 CELLS TO TOXIC EFFECTS OF RICIN AND ABRIN

被引：2

作者：

BESANCON, F ^{[1
]}

ANKEL, H ^{[1
]}

机构：

[1] MED COLL WISCONSIN,DEPT BIOCHEM,MILWAUKEE,WI 53226

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 88卷 / 03期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0006-291X(79)91481-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Approximately two to four times higher concentrations of the plant toxins abrin and ricin are required to inhibit protein synthesis in interferon-resistant L-1210R cells to the same degree as in interferon-sensitive L-1210S cells. However, amounts of interferon 10-fold higher than those required for protection from viral infection fail to show any effect on ricin intoxication of L-1210S cells. © 1979.

引用

页码：818 / 825

页数：8

共 17 条

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OLSNES S, 1976, J BIOL CHEM, V251, P3985

[12]

OLSNES S, 1977, RECEPTORS RECOGNIT B, V1, P129

[13] IMMUNOPRECIPITATION AND PARTIAL CHARACTERIZATION OF DIPHTHERIA TOXIN-BINDING GLYCOPROTEINS FROM SURFACE OF GUINEA-PIG CELLS [J].