HIGH-RESOLUTION X-RAY ANALYSES OF RENIN INHIBITOR-ASPARTIC PROTEINASE COMPLEXES

被引：133

作者：

FOUNDLING, SI

COOPER, J

WATSON, FE

CLEASBY, A

PEARL, LH

SIBANDA, BL

HEMMINGS, A

WOOD, SP

BLUNDELL, TL

VALLER, MJ

NOREY, CG

KAY, J

BOGER, J

DUNN, BM

LECKIE, BJ

JONES, DM

ATRASH, B

HALLETT, A

SZELKE, M

机构：

[1] UNIV WALES UNIV COLL CARDIFF,DEPT BIOCHEM,CARDIFF CF1 1XL,S GLAM,WALES

[2] MERCK SHARP & DOHME RES LABS,RAHWAY,NJ 07065

[3] UNIV FLORIDA,COLL MED,DEPT BIOCHEM & MOLEC BIOL,GAINESVILLE,FL 32610

[4] WESTERN INFIRM,BLOOD PRESSURE UNIT,GLASGOW G11 6NT,SCOTLAND

[5] ROYAL POSTGRAD MED SCH,LONDON W12 0HS,ENGLAND

来源：

NATURE | 1987年 / 327卷 / 6120期

关键词：

D O I：

10.1038/327349a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：349 / 352

页数：4

共 28 条

[1] 3-DIMENSIONAL STRUCTURE OF HUMAN RENIN [J].

AKAHANE, K ;

UMEYAMA, H ;

NAKAGAWA, S ;

MORIGUCHI, I ;

HIROSE, S ;

IIZUKA, K ;

MURAKAMI, K .

HYPERTENSION, 1985, 7 (01) :3-12

[2] 3-DIMENSIONAL STRUCTURE, SPECIFICITY AND CATALYTIC MECHANISM OF RENIN [J].

BLUNDELL, T ;

SIBANDA, BL ;

PEARL, L .

NATURE, 1983, 304 (5923) :273-275

[3]

BLUNDELL TL, 1985, ASPARTIC PROTEINASES, P151

[4] NOVEL RENIN INHIBITORS CONTAINING THE AMINO-ACID STATINE [J].

BOGER, J ;

LOHR, NS ;

ULM, EH ;

POE, M ;

BLAINE, EH ;

FANELLI, GM ;

LIN, TY ;

PAYNE, LS ;

SCHORN, TW ;

LAMONT, BI ;

VASSIL, TC ;

STABILITO, II ;

VEBER, DF ;

RICH, DH ;

BOPARI, AS .

NATURE, 1983, 303 (5912) :81-84

[5]

Boger J., 1985, ASPARTIC PROTEINASES, P401

[6] 3-DIMENSIONAL STRUCTURE OF THE COMPLEX OF THE RHIZOPUS-CHINENSIS CARBOXYL PROTEINASE AND PEPSTATIN AT 2.5-A RESOLUTION [J].

BOTT, R ;

SUBRAMANIAN, E ;

DAVIES, DR .

BIOCHEMISTRY, 1982, 21 (26) :6956-6962

[7] CONSTRUCTION OF A MODEL FOR THE 3-DIMENSIONAL STRUCTURE OF HUMAN RENAL RENIN [J].

CARLSON, W ;

KARPLUS, M ;

HABER, E .

HYPERTENSION, 1985, 7 (01) :13-26

[8] THE SYNTHESIS, PURIFICATION, AND EVALUATION OF A CHROMOPHORIC SUBSTRATE FOR PEPSIN AND OTHER ASPARTYL PROTEASES - DESIGN OF A SUBSTRATE BASED ON SUBSITE PREFERENCES [J].

DUNN, BM ;

KAMMERMANN, B ;

MCCURRY, KR .

ANALYTICAL BIOCHEMISTRY, 1984, 138 (01) :68-73

[9]

DUNN BM, 1985, ASPARTIC PROTEINASES, P221

[10]

HABER E, 1979, FED PROC, V38, P2768

← 1 2 3 →