SITE-DIRECTED MUTAGENESIS OF HUMAN BETA-ADRENERGIC RECEPTORS - SUBSTITUTION OF ASPARTIC ACID-130 BY ASPARAGINE PRODUCES A RECEPTOR WITH HIGH-AFFINITY AGONIST BINDING THAT IS UNCOUPLED FROM ADENYLATE-CYCLASE

被引:134
作者
FRASER, CM
CHUNG, FZ
WANG, CD
VENTER, JC
机构
关键词
D O I
10.1073/pnas.85.15.5478
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
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页码:5478 / 5482
页数:5
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