T-CELLS AND EOSINOPHILS IN THE PATHOGENESIS OF ASTHMA

被引：537

作者：

CORRIGAN, CJ

KAY, AB

机构：

[1] C.J. Corrigan and A.B. Kay are, the Dept of Allergy and Clinical Immunology, National Heart and Lung Institute, London, SW3 6LY, Dovehouse Street

来源：

IMMUNOLOGY TODAY | 1992年 / 13卷 / 12期

关键词：

D O I：

10.1016/0167-5699(92)90026-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Persistent asthma is characterized by chronic inflammation of the bronchial mucosa, where T cells and eosinophils are prominent. This article summarizes the evidence that asthmatic bronchial inflammation is initiated and propagated by cytokines secreted by activated T cells and other cells, and describes how the release of specific cytokines could result in local preferential accumulation and activation of eosinophils.

引用

页码：501 / 507

页数：7

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