DEXAMETHASONE PARTIALLY REDUCES AND 2-PERCENT SALINE-TREATMENT ABOLISHED ELECTRO-ACUPUNCTURE ANALGESIA - THESE FINDINGS IMPLICATE PITUITARY ENDORPHINS

被引：48

作者：

CHENG, R

POMERANZ, B

YU, G

机构：

[1] Department of Zoology, University of Toronto, Toronto

来源：

LIFE SCIENCES | 1979年 / 24卷 / 16期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0024-3205(79)90031-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Dexamethasone, a cortisol analogue which inhibits ACTH and endorphin release in a negative feedback system, partially reduces electroacupuncture analgesia (EAA) in mice. In addition, mice forced to drink 2% saline for 3 days (this reduces pituitary endorphin levels) had a complete loss of EAA. These two experiments support our previous finding that hypophysectomy abolishes EAA. Altogether, these results implicate pituitary endorphins in EAA. © 1979.

引用

页码：1481 / 1486

页数：6

共 20 条

[11] EFFECT OF DEHYDRATION ON ENDOGENOUS OPIATE CONTENT OF RAT NEURO-INTERMEDIATE LOBE [J].