IMMUNOSUPPRESSIVE EFFECTS OF ALLOGENEIC BLOOD-TRANSFUSIONS - IMPLICATIONS FOR THE PATIENT WITH A MALIGNANCY

被引：46

作者：

BORDIN, JO

BLAJCHMAN, MA

机构：

[1] MCMASTER UNIV, HAMILTON, ON, CANADA

[2] CANADIAN RED CROSS SOC, HAMILTON CTR, HAMILTON, ON, CANADA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 1995年 / 9卷 / 01期

关键词：

D O I：

10.1016/S0889-8588(18)30117-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Allogeneic blood transfusions (ABT) are associated with immunomodulatory effects to the recipients. Perioperative ABT thus may adversely affect overall prognosis in patients with a malignancy. ABT have been shown to be associated also with an increased risk for bacterial infections. In animal models, the ABT tumor growth-promoting effect has been shown to be related to leukocytes and is ameliorated by leukodepletion. In humans, such an effect has been reported; however, clearcut clinical evidence for the tumor growth-promoting effect of ABT has not yet been proved.

引用

页码：205 / 218

页数：14

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