REGULATORY MECHANISMS THAT COORDINATE SKELETAL-MUSCLE DIFFERENTIATION AND CELL-CYCLE WITHDRAWAL

被引：315

作者：

LASSAR, AB

SKAPEK, SX

NOVITCH, B

机构：

[1] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115

来源：

CURRENT OPINION IN CELL BIOLOGY | 1994年 / 6卷 / 06期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0955-0674(94)90046-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Skeletal muscle differentiation entails the coupling of muscle-specific gene expression to terminal withdrawal from the cell cycle. Several models have recently been proposed which attempt to explain how regulated expression and function of myogenic transcription factors ensures that proliferation and differentiation of skeletal muscle cells are mutually exclusive processes.

引用

收藏

页码：788 / 794

页数：7

相关论文

共 55 条

[1] E1A-ASSOCIATED P300 AND CREB-ASSOCIATED CBP BELONG TO A CONSERVED FAMILY OF COACTIVATORS [J].

ARANY, Z ;

SELLERS, WR ;

LIVINGSTON, DM ;

ECKNER, R .

CELL, 1994, 77 (06) :799-800

[2] THE PROTEIN ID - A NEGATIVE REGULATOR OF HELIX-LOOP-HELIX DNA-BINDING PROTEINS [J].

BENEZRA, R ;

DAVIS, RL ;

LOCKSHON, D ;

TURNER, DL ;

WEINTRAUB, H .

CELL, 1990, 61 (01) :49-59

[3] POSITIVE CONTROL MUTATIONS IN THE MYOD BASIC REGION FAIL TO SHOW COOPERATIVE DNA-BINDING AND TRANSCRIPTIONAL ACTIVATION IN-VITRO [J].

BENGAL, E ;

FLORES, O ;

RANGARAJAN, PN ;

CHEN, A ;

WEINTRAUB, H ;

VERMA, IM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (13) :6221-6225

[4] FUNCTIONAL ANTAGONISM BETWEEN C-JUN AND MYOD PROTEINS - A DIRECT PHYSICAL ASSOCIATION [J].

BENGAL, E ;

RANSONE, L ;

SCHARFMANN, R ;

DWARKI, VJ ;

TAPSCOTT, SJ ;

WEINTRAUB, H ;

VERMA, IM .

CELL, 1992, 68 (03) :507-519

[5] INHIBITION OF MUSCLE DIFFERENTIATION BY THE ADENOVIRUS E1A-PROTEIN - REPRESSION OF THE TRANSCRIPTIONAL ACTIVATING FUNCTION OF THE HLH PROTEIN MYF-5 [J].

BRAUN, T ;

BOBER, E ;

ARNOLD, HH .

GENES & DEVELOPMENT, 1992, 6 (05) :888-902

[6] TRANSFORMING GROWTH-FACTOR-BETA REPRESSES THE ACTIONS OF MYOGENIN THROUGH A MECHANISM INDEPENDENT OF DNA-BINDING [J].

BRENNAN, TJ ;

EDMONDSON, DG ;

LI, L ;

OLSON, EN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (09) :3822-3826

[7] REVERSAL OF TERMINAL DIFFERENTIATION AND CONTROL OF DNA-REPLICATION - CYCLIN-A AND CDK2 SPECIFICALLY LOCALIZE AT SUBNUCLEAR SITES OF DNA-REPLICATION [J].

CARDOSO, MC ;

LEONHARDT, H ;

NADALGINARD, B .

CELL, 1993, 74 (06) :979-992

[8]

CARUSO M, 1993, ONCOGENE, V8, P267

[9] HETEROKARYON ANALYSIS OF MUSCLE DIFFERENTIATION - REGULATION OF THE POSTMITOTIC STATE [J].

CLEGG, CH ;

HAUSCHKA, SD .

JOURNAL OF CELL BIOLOGY, 1987, 105 (02) :937-947

[10]

CUSELLADEANGELIS MG, 1994, DEVELOPMENT, V120, P925

← 1 2 3 4 5 6 →