CELL-DEATH BY APOPTOSIS AND ITS PROTECTIVE ROLE AGAINST DISEASE

被引：409

作者：

BURSCH, W

OBERHAMMER, F

SCHULTEHERMANN, R

机构：

[1] W. Barsch, F. Oberhammer and R. Schuhe-Hermann are all, the Institut für Tumorbiologie-Krebsforschung der Universität Wien, A1090 Wien

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1992年 / 13卷 / 06期

关键词：

D O I：

10.1016/0165-6147(92)90077-J

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The involvement of cell death in control of tissue growth has long been neglected, but the description of apoptosis as cellular 'suicide', the functional opposite of mitosis, is now attracting more attention to this phenomenon. Physiologically unwanted cells are removed by apoptosis, and toxic chemicals and drugs may enhance or inhibit this type of cell death. These findings are providing new insights into the pathophysiology of a variety of diseases, and suggesting new therapeutic strategies.

引用

页码：245 / 251

页数：7

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