CYTOCHROME-P-450 CATALYSIS - RADICAL INTERMEDIATES AND DEHYDROGENATION REACTIONS

被引：94

作者：

DEMONTELLANO, PRO

机构：

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1989年 / 10卷 / 09期

关键词：

D O I：

10.1016/0165-6147(89)90007-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：354 / 359

页数：6

共 27 条

[11]

KOMIVES EA, 1987, J BIOL CHEM, V262, P9793

[12] A THEORETICAL-STUDY ON THE METABOLIC-ACTIVATION OF PARACETAMOL BY CYTOCHROME-P-450 - INDICATIONS FOR A UNIFORM OXIDATION MECHANISM [J].

KOYMANS, L ;

VANLENTHE, JH ;

VANDESTRAAT, R ;

DENKELDER, GMDO ;

VERMEULEN, NPE .

CHEMICAL RESEARCH IN TOXICOLOGY, 1989, 2 (01) :60-66

[13] 4-ALKYL RADICAL EXTRUSION IN THE CYTOCHROME-P-450-CATALYZED OXIDATION OF 4-ALKYL-1,4-DIHYDROPYRIDINES [J].

LEE, JS ;

JACOBSEN, NE ;

DEMONTELLANO, PRO .

BIOCHEMISTRY, 1988, 27 (20) :7703-7710

[14] EVIDENCE FOR A CYTOCHROME-P-450 CATALYZED ALLYLIC REARRANGEMENT WITH DOUBLE-BOND TOPOMERIZATION [J].

MCCLANAHAN, RH ;

HUITRIC, AC ;

PEARSON, PG ;

DESPER, JC ;

NELSON, SD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (06) :1979-1981

[15]

NAGATA K, 1986, DRUG METAB DISPOS, V14, P559

[16] ISOLATION OF 19,20-DEHYDROPROSTAGLANDINS-E1 AND 19,20-DEHYDROPROSTAGLANDINS-E2 IN HUMAN SEMINAL FLUID AND FURTHER-STUDIES ON 18,19-DEHYDROPROSTAGLANDINS-E1 AND 18,19-DEHYDROPROSTAGLANDINS-E2 [J].

OLIW, EH ;

BENTHIN, G ;

HAMBERG, M .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1987, 258 (01) :272-286

[17]

OSTOVIC D, 1989, IN PRESS J AM CH AUG

[18]

RETTIE AE, 1988, J BIOL CHEM, V263, P13733

[19] CYTOCHROME-P-450 - CATALYZED FORMATION OF DELTA-4-VPA, A TOXIC METABOLITE OF VALPROIC ACID [J].

RETTIE, AE ;

RETTENMEIER, AW ;

HOWALD, WN ;

BAILLIE, TA .

SCIENCE, 1987, 235 (4791) :890-893

[20] LABELED 1,N6-ETHENOADENOSINE AND 3,N4-ETHENOCYTIDINE IN HEPATIC RNA OF MICE GIVEN [ETHYL-1,2-H-3 OR ETHYL-1-C-14] ETHYL CARBAMATE (URETHANE) [J].

RIBOVICH, ML ;

MILLER, JA ;

MILLER, EC ;

TIMMINS, LG .

CARCINOGENESIS, 1982, 3 (05) :539-546

← 1 2 3 →