TARGETING OF NONEXPRESSED GENES IN EMBRYONIC STEM-CELLS VIA HOMOLOGOUS RECOMBINATION

被引：91

作者：

JOHNSON, RS

SHENG, M

GREENBERG, ME

KOLODNER, RD

PAPAIOANNOU, VE

SPIEGELMAN, BM

机构：

[1] HARVARD UNIV,SCH MED,DANA FARBER CANC INST,BOSTON,MA 02115

[2] HARVARD UNIV,SCH MED,DEPT MICROBIOL & MOLEC GENET,BOSTON,MA 02115

[3] HARVARD UNIV,SCH MED,DEPT BIOL CHEM & MOLEC PHARMACOL,BOSTON,MA 02115

[4] TUFTS UNIV,SCH MED,DEPT PATHOL,BOSTON,MA 02111

[5] TUFTS UNIV,SCH VET MED,BOSTON,MA 02111

来源：

SCIENCE | 1989年 / 245卷 / 4923期

关键词：

D O I：

10.1126/science.2506639

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1234 / 1236

页数：3

共 29 条

[11]

DOGLIO A, 1986, BIOCHEM J, V238, P123, DOI 10.1042/bj2380123

[12] ESTABLISHMENT IN CULTURE OF PLURIPOTENTIAL CELLS FROM MOUSE EMBRYOS [J].

EVANS, MJ ;

KAUFMAN, MH .

NATURE, 1981, 292 (5819) :154-156

[13] CUT, PASTE, AND SAVE - NEW APPROACHES TO ALTERING SPECIFIC GENES IN MICE [J].

FROHMAN, MA ;

MARTIN, GR .

CELL, 1989, 56 (02) :145-147

[14] IDENTIFICATION OF PHOSPHORYLATED 422(AP2) PROTEIN AS PP15, THE 15-KILODALTON TARGET OF THE INSULIN-RECEPTOR TYROSINE KINASE IN 3T3-L1 ADIPOCYTES [J].

HRESKO, RC ;

BERNIER, M ;

HOFFMAN, RD ;

FLORESRIVEROS, JR ;

LIAO, K ;

LAIRD, DM ;

LANE, MD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (23) :8835-8839

[15] PRODUCTION OF A MUTATION IN MOUSE EN-2 GENE BY HOMOLOGOUS RECOMBINATION IN EMBRYONIC STEM-CELLS [J].

JOYNER, AL ;

SKARNES, WC ;

ROSSANT, J .

NATURE, 1989, 338 (6211) :153-156

[16] DISRUPTION OF THE PROTO-ONCOGENE INT-2 IN MOUSE EMBRYO-DERIVED STEM-CELLS - A GENERAL STRATEGY FOR TARGETING MUTATIONS TO NON-SELECTABLE GENES [J].

MANSOUR, SL ;

THOMAS, KR ;

CAPECCHI, MR .

NATURE, 1988, 336 (6197) :348-352

[17] ISOLATION OF A PLURIPOTENT CELL-LINE FROM EARLY MOUSE EMBRYOS CULTURED IN MEDIUM CONDITIONED BY TERATOCARCINOMA STEM-CELLS [J].

MARTIN, GR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (12) :7634-7638

[18]

MATARESE V, 1988, J BIOL CHEM, V263, P14544

[19] THE NUCLEOTIDE-SEQUENCE AND TRANSCRIPT MAP OF THE HERPES-SIMPLEX VIRUS THYMIDINE KINASE GENE [J].

MCKNIGHT, SL .

NUCLEIC ACIDS RESEARCH, 1980, 8 (24) :5949-5964

[20]

PAPAIOANNOU VE, 1978, J EMBRYOL EXP MORPH, V44, P93

← 1 2 3 →