THE SYNTHESIS OF ISOPRENOID (PHOSPHINYLMETHYL)PHOSPHONATES

被引：48

作者：

BILLER, SA

FORSTER, C

机构：

来源：

TETRAHEDRON | 1990年 / 46卷 / 19期

关键词：

D O I：

10.1016/S0040-4020(01)87856-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthetic route to isoprenoid (phosphinylmethyl)phosphonates (PMPs), stable analogues of the biologically important diphosphates, is described. This method involves the reaction of an α-phosphonate carbanion with an isoprenoid phosphonochloridate to provide the PMP triesters, followed by ester cleavage with TMSBr or TMSI. 13C NMR, 31P NMR, 19F NMR and FAB-MS data were employed for the characterization of PMP salts and triesters. © 1990.

引用

页码：6645 / 6658

页数：14