CHROMATIN AS AN ESSENTIAL PART OF THE TRANSCRIPTIONAL MECHANISM

被引：827

作者：

FELSENFELD, G

机构：

[1] Laboratory of Molecular Biology, National Institutes of Health, Bethesda

来源：

NATURE | 1992年 / 355卷 / 6357期

关键词：

D O I：

10.1038/355219a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The increasingly detailed biochemical definition of the protein complexes that regulate gene transcription has led to the re-emergence of questions about the role of histones. Much recent evidence suggests that transcriptional activation requires that transcription factors successfully compete with histones for binding to promoters, and that there may be more than one mechanism by which this is achieved.

引用

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页码：219 / 224

页数：6

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