OLIGODEOXYNUCLEOSIDE METHYLPHOSPHONATES - SYNTHESIS AND ENZYMATIC DEGRADATION

被引：121

作者：

AGRAWAL, S ^{[1
]}

GOODCHILD, J ^{[1
]}

机构：

[1] WORCESTER FDN EXPTL BIOL,222 MAPLE AVE,SHREWSBURY,MA 01545

来源：

TETRAHEDRON LETTERS | 1987年 / 28卷 / 31期

关键词：

D O I：

10.1016/S0040-4039(00)95529-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3539 / 3542

页数：4

共 15 条

[1] SYNTHESIS AND ENZYMATIC PROPERTIES OF DEOXYRIBOOLIGONUCLEOTIDES CONTAINING METHYL AND PHENYLPHOSPHONATE LINKAGES [J].

AGARWAL, KL ;

RIFTINA, F .

NUCLEIC ACIDS RESEARCH, 1979, 6 (09) :3009-3024

[2] INHIBITION OF VESICULAR STOMATITIS-VIRUS PROTEIN-SYNTHESIS AND INFECTION BY SEQUENCE-SPECIFIC OLIGODEOXYRIBONUCLEOSIDE METHYLPHOSPHONATES [J].

AGRIS, CH ;

BLAKE, KR ;

MILLER, PS ;

REDDY, MP ;

TSO, POP .

BIOCHEMISTRY, 1986, 25 (20) :6268-6275

[3] NUCLEOTIDE CHEMISTRY .8. SYNTHESIS OF OLIGODEOXYNUCLEOTIDES AND OLIGODEOXYNUCLEOTIDE ANALOGS USING PHOSPHORAMIDITE INTERMEDIATES [J].

DORMAN, MA ;

NOBLE, SA ;

MCBRIDE, LJ ;

CARUTHERS, MH .

TETRAHEDRON, 1984, 40 (01) :95-102

[4] ALKYL PHOSPHOTRIESTER MODIFIED OLIGODEOXYRIBONUCLEOTIDES .5. SYNTHESIS AND ABSOLUTE-CONFIGURATION OF RP AND SP DIASTEREOMERS OF AN ETHYL PHOSPHOTRIESTER (ET) MODIFIED ECORI RECOGNITION SEQUENCE, D[GGAA(ET)TTCC] - A SYNTHETIC APPROACH TO REGIOSPECIFIC AND STEREOSPECIFIC ETHYLATION-INTERFERENCE STUDIES [J].

GALLO, KA ;

SHAO, KL ;

PHILLIPS, LR ;

REGAN, JB ;

KOZIOLKIEWICZ, M ;

UZNANSKI, B ;

STEC, WJ ;

ZON, G .

NUCLEIC ACIDS RESEARCH, 1986, 14 (18) :7405-7420

[5] SYNTHESIS OF DEOXYNUCLEOSIDE METHYLPHOSPHONATES VIA A PHOSPHONAMIDITE APPROACH [J].

JAGER, A ;

ENGELS, J .

TETRAHEDRON LETTERS, 1984, 25 (14) :1437-1440

[6] SYNTHESIS OF NUCLEIC-ACID METHYLPHOSPHONATES VIA THE 1-HYDROXYBENZOTRIAZOLE PHOSPHOTRIESTER APPROACH [J].

MARUGG, JE ;

DEVROOM, E ;

DREEF, CE ;

TROMP, M ;

VANDERMAREL, GA ;

VANBOOM, JH .

NUCLEIC ACIDS RESEARCH, 1986, 14 (05) :2171-2185

[7] PREPARATION OF OLIGODEOXYRIBONUCLEOSIDE METHYLPHOSPHONATES ON A POLYSTYRENE SUPPORT [J].

MILLER, PS ;

AGRIS, CH ;

MURAKAMI, A ;

REDDY, PM ;

SPITZ, SA ;

TSO, POP .

NUCLEIC ACIDS RESEARCH, 1983, 11 (18) :6225-6242

[8] NON-IONIC NUCLEIC-ACID ANALOGS - SYNTHESIS AND CHARACTERIZATION OF DIDEOXYRIBONUCLEOSIDE METHYLPHOSPHONATES [J].

MILLER, PS ;

YANO, J ;

YANO, E ;

CARROLL, C ;

JAYARAMAN, K ;

TSO, POP .

BIOCHEMISTRY, 1979, 18 (23) :5134-5143

[9] SOLID-PHASE SYNTHESES OF OLIGODEOXYRIBONUCLEOSIDE METHYLPHOSPHONATES [J].

MILLER, PS ;

REDDY, MP ;

MURAKAMI, A ;

BLAKE, KR ;

LIN, SB ;

AGRIS, CH .

BIOCHEMISTRY, 1986, 25 (18) :5092-5097

[10] USE OF METHYLPHOSPHONIC DICHLORIDE FOR THE SYNTHESIS OF OLIGONUCLEOSIDE METHYLPHOSPHONATES [J].

MILLER, PS ;

AGRIS, CH ;

BLANDIN, M ;

MURAKAMI, A ;

REDDY, PM ;

SPITZ, SA ;

TSO, POP .

NUCLEIC ACIDS RESEARCH, 1983, 11 (15) :5189-5204

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