SEVERE INFECTIOUS-MONONUCLEOSIS LIKE SYNDROME AND PRIMARY HUMAN HERPESVIRUS-6 INFECTION IN AN ADULT

被引：117

作者：

AKASHI, K

EIZURU, Y

SUMIYOSHI, Y

MINEMATSU, T

HARA, S

HARADA, M

KIKUCHI, M

NIHO, Y

MINAMISHIMA, Y

机构：

[1] HARASANSHIN GEN HOSP,DEPT DERMATOL,FUKUOKA,JAPAN

[2] MIYAZAKI MED COLL,DEPT MICROBIOL,MIYAZAKI 88916,JAPAN

[3] FUKUOKA UNIV,SCH MED,DEPT PATHOL 1,FUKUOKA 81401,JAPAN

[4] KYUSHU UNIV,DEPT INTERNAL MED 1,FUKUOKA 812,JAPAN

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 1993年 / 329卷 / 03期

关键词：

D O I：

10.1056/NEJM199307153290304

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Human herpesvirus 6 (HHV-6) was first isolated from patients with the acquired immunodeficiency syndrome or lymphoproliferative diseases and was named human B-lymphotropic virus1. However, later studies revealed that the virus is T-lymphotropic in vitro2 and in vivo3. Recently, two genotypes of HHV-6 (type A and type B) have been distinguished on the basis of their restriction polymorphism4–6. HHV-6 has been identified as the etiologic agent of exanthem subitum in infants,7 and an acute febrile illness in young children8. Most people are seropositive for HHV-6 by the age of three years9,10. HHV-6 also produces… © 1993, Massachusetts Medical Society. All rights reserved.

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页码：168 / 171

页数：4

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