HUMAN HERPESVIRUS-6 IN SALIVARY-GLANDS

被引：157

作者：

FOX, JD

BRIGGS, M

WARD, PA

TEDDER, RS

机构：

[1] Department of Medical Microbiology, University College, Middlesex School of Medicine, London, W1 P 7PN

来源：

LANCET | 1990年 / 336卷 / 8715期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0140-6736(90)93392-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In an investigation of the role of saliva in the transmission of human herpesvirus 6 (HHV6) sections of salivary gland tissue were screened for HHV6-specific DNA by in-situ hybridisation and for HHV6-specific protein by immunohistochemical staining with monoclonal antibodies against the virus. All of nine submandibular glands and one of four parotid glands showed the presence of H HV6 genome and expressed protein by these techniques. The findings are consistent with transmission of HHV6 by saliva and suggest that salivary gland tissue is a site of replication of the virus and a potential site for HHV6 persistence. © 1990.

引用

页码：590 / 593

页数：4

共 23 条

[1]

ASANO Y, 1989, LANCET, V2, P1391

[2]

BRIGGS M, 1988, LANCET, V1, P1058

[3] POLYMERASE CHAIN-REACTION AMPLIFICATION AND INSITU HYBRIDIZATION FOR THE DETECTION OF HUMAN B-LYMPHOTROPIC VIRUS [J].