GAPS FOR RHO-RELATED GTPASES

被引：214

作者：

LAMARCHE, N ^{[1
]}

HALL, A ^{[1
]}

机构：

[1] UCL, DEPT BIOCHEM, LONDON WC1E 6BT, ENGLAND

来源：

TRENDS IN GENETICS | 1994年 / 10卷 / 12期

关键词：

D O I：

10.1016/0168-9525(94)90114-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Ras-related GTP-binding proteins (GTPases) of the rho subfamily play important roles in regulating the organization of the actin cytoskeleton. A large number of multifunctional proteins that can stimulate their intrinsic GTPase activity have been identified Here, we discuss the nature of such GTPase-activating proteins (GAPs) and their potential importance for cell signalling.

引用

页码：436 / 440

页数：5

共 43 条

[1]

ADAMS JM, 1992, ONCOGENE, V7, P611

[2] A DROSOPHILA ROTUND TRANSCRIPT EXPRESSED DURING SPERMATOGENESIS AND IMAGINAL DISK MORPHOGENESIS ENCODES A PROTEIN WHICH IS SIMILAR TO HUMAN RAC GTPASE-ACTIVATING (RACGAP) PROTEINS [J].