BASIC FIBROBLAST GROWTH-FACTOR (BFGF, FGF-2) IMMUNOREACTIVITY EXISTS IN THE NORADRENALINE, ADRENALINE AND 5-HT NERVE-CELLS OF THE RAT-BRAIN

被引：37

作者：

CHADI, G

TINNER, B

AGNATI, LF

FUXE, K

机构：

[1] KAROLINSKA INST,DEPT HISTOL & NEUROBIOL,BOX 60400,S-10401 STOCKHOLM 60,SWEDEN

[2] UNIV MODENA,DEPT HUMAN PHYSIOL,I-41100 MODENA,ITALY

来源：

NEUROSCIENCE LETTERS | 1993年 / 160卷 / 02期

关键词：

BASIC FIBROBLAST GROWTH FACTOR; IMMUNOCYTOCHEMISTRY; COEXISTENCE; NORADRENALINE; ADRENALINE; 5-HYDROXYTRYPTAMINE; TYROSINE HYDROXYLASE; BRAIN;

D O I：

10.1016/0304-3940(93)90406-B

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

By means of two colour immunofluorescence procedures it has been possible to demonstrate in the rat brain the coexistence of TH and bFGF immunoreactivities (IRs) in the perikarya of large numbers of noradrenaline (NA) nerve cells of the locus coeruleus and of the NA cell groups A1, A5 and A7 and in many perikarya of the adrenaline (A) cell groups Cl, C2 and C3. The coexistence of 5-hydroxytryptamine (5-HT) and bFGF IRs was demonstrated in the perikarya of large numbers of 5-HT nerve cells of practically all raphe nuclei. These results open up the possibility that bFGF may have a trophic role in the NA, A and 5-HT cell groups of the rat brain.

引用

页码：171 / 176

页数：6

共 35 条

[1] THE FIBROBLAST GROWTH-FACTOR FAMILY - AN OVERVIEW [J].