RELATION BETWEEN MATERNAL HEMOGLOBIN AND PLACENTAL HORMONE CONCENTRATIONS IN EARLY-PREGNANCY

被引：36

作者：

WHEELER, T ^{[1
]}

SOLLERO, C ^{[1
]}

ALDERMAN, S ^{[1
]}

LANDEN, J ^{[1
]}

ANTHONY, F ^{[1
]}

OSMOND, C ^{[1
]}

机构：

[1] SOUTHAMPTON GEN HOSP, MRC, ENVIRONM EPIDEMIOL UNIT, SOUTHAMPTON SO9 4XY, HANTS, ENGLAND

来源：

LANCET | 1994年 / 343卷 / 8896期

关键词：

D O I：

10.1016/S0140-6736(94)91461-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Environmental factors that influence placental development are of particular interest because of the reported association between adult hypertension, low birthweight, and large placental size. Maternal anaemia is one environmental factor that is associated with an increase in placental size at birth. We have examined the relation between haematological status and plasma concentrations of chorionic gonadotropin (hCG) and placental lactogen (hPL) in 175 women at about 10 weeks of pregnancy. There were significant negative correlations between maternal haemoglobin concentration and the levels of hCG (p=0.03) and hPL (p=0.02). Although 21% of women had low iron stores (ferritin < 13 mu g/L), no relation was found between serum ferritin and the two placental hormones. There was no association between plasma volume (calculated from maternal weight and height) and hCG or hPL concentrations.

引用

页码：511 / 513

页数：3