HISTONES AS REGULATORS OF GENES

被引：61

作者：

GRUNSTEIN, M

机构：

来源：

SCIENTIFIC AMERICAN | 1992年 / 267卷 / 04期

关键词：

D O I：

10.1038/scientificamerican1092-68

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Until recently, these proteins in the nuclei of cells were regarded as little more than passive spindles around which the crucial molecules of DNA wound. Their task turns out to be more complex: histones are vital participants in the expression and suppression of genes. Insights into their role should help explain how the process can go awry and lead to diseases such as cancer.

引用

页码：68 / B74

共 4 条

[1] YEAST HISTONE H4 N-TERMINAL SEQUENCE IS REQUIRED FOR PROMOTER ACTIVATION INVIVO [J].