REGULATION OF ACTIVITY OF LOW-DENSITY LIPOPROTEIN RECEPTOR IN HUMAN FIBROBLASTS

被引：454

作者：

BROWN, MS ^{[1
]}

GOLDSTEIN, JL ^{[1
]}

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT INTERN MED,DIV MED GENET,DALLAS,TX 75235

来源：

CELL | 1975年 / 6卷 / 03期

关键词：

D O I：

10.1016/0092-8674(75)90182-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：307 / 316

页数：10

共 17 条

[1]

BROWN MS, 1974, J BIOL CHEM, V249, P789

[2] ROLE OF LOW-DENSITY LIPOPROTEIN RECEPTOR IN REGULATING CONTENT OF FREE AND ESTERIFIED CHOLESTEROL IN HUMAN FIBROBLASTS [J].

BROWN, MS ;

FAUST, JR ;

GOLDSTEIN, JL .

JOURNAL OF CLINICAL INVESTIGATION, 1975, 55 (04) :783-793

[3] FAMILIAL HYPERCHOLESTEROLEMIA - DEFECTIVE BINDING OF LIPOPROTEINS TO CULTURED FIBROBLASTS ASSOCIATED WITH IMPAIRED REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE-ACTIVITY [J].

BROWN, MS ;

GOLDSTEIN, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (03) :788-792

[4]

BROWN MS, 1975, J BIOL CHEM, V250, P4025

[5]

BROWN MS, 1974, J BIOL CHEM, V249, P7306

[6] EXPRESSION OF FAMILIAL HYPERCHOLESTEROLEMIA GENE IN HETEROZYGOTES - MECHANISM FOR A DOMINANT DISORDER IN MAN [J].

BROWN, MS ;

GOLDSTEIN, JL .

SCIENCE, 1974, 185 (4145) :61-63

[7] RECEPTOR-DEPENDENT HYDROLYSIS OF CHOLESTERYL ESTERS CONTAINED IN PLASMA LOW-DENSITY LIPOPROTEIN [J].

BROWN, MS ;

DANA, SE ;

GOLDSTEIN, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (08) :2925-2929

[8] INHIBITION OF CELL-GROWTH BY OXYGENATED DERIVATIVES OF CHOLESTEROL [J].

CHEN, HW ;

KANDUTSCH, AA ;

WAYMOUTH, C .

NATURE, 1974, 251 (5474) :419-421

[9] FAMILIAL HYPERCHOLESTEROLEMIA - IDENTIFICATION OF A DEFECT IN REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE-ACTIVITY ASSOCIATED WITH OVERPRODUCTION OF CHOLESTEROL [J].

GOLDSTEIN, JL ;

BROWN, MS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (10) :2804-2808

[10]

GOLDSTEIN JL, 1974, J BIOL CHEM, V249, P5153

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