ROLE OF LOW-DENSITY LIPOPROTEIN RECEPTOR IN REGULATING CONTENT OF FREE AND ESTERIFIED CHOLESTEROL IN HUMAN FIBROBLASTS

被引：327

作者：

BROWN, MS ^{[1
]}

FAUST, JR ^{[1
]}

GOLDSTEIN, JL ^{[1
]}

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT INTERN MED,DALLAS,TX 75235

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1975年 / 55卷 / 04期

关键词：

D O I：

10.1172/JCI107989

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：783 / 793

页数：11

共 33 条

[1] CHOLESTEROL UPTAKE FROM DOUBLY LABELED ALPHA-LIPOPROTEINS BY CELLS IN TISSUE-CULTURE [J].

BAILEY, JM ;

BUTLER, J .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1973, 159 (01) :580-581

[2]

BAILEY JM, 1973, CIBA F S, V12, P63

[3] REGULATION OF CELLULAR STEROL FLUX AND SYNTHESIS BY HUMAN-SERUM LIPOPROTEINS [J].

BATES, SR ;

ROTHBLAT, GH .

BIOCHIMICA ET BIOPHYSICA ACTA, 1974, 360 (01) :38-55

[4]

BROWN MS, 1974, J BIOL CHEM, V249, P789

[5] REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE-ACTIVITY IN HUMAN FIBROBLASTS BY LIPOPROTEINS [J].

BROWN, MS ;

DANA, SE ;

GOLDSTEIN, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (07) :2162-2166

[6] FAMILIAL HYPERCHOLESTEROLEMIA - DEFECTIVE BINDING OF LIPOPROTEINS TO CULTURED FIBROBLASTS ASSOCIATED WITH IMPAIRED REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE-ACTIVITY [J].

BROWN, MS ;

GOLDSTEIN, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (03) :788-792

[7]

BROWN MS, 1974, J BIOL CHEM, V249, P7306

[8] EXPRESSION OF FAMILIAL HYPERCHOLESTEROLEMIA GENE IN HETEROZYGOTES - MECHANISM FOR A DOMINANT DISORDER IN MAN [J].

BROWN, MS ;

GOLDSTEIN, JL .

SCIENCE, 1974, 185 (4145) :61-63

[9] EXCHANGE OF UNESTERIFIED CHOLESTEROL BETWEEN HUMAN LOW-DENSITY LIPOPROTEINS AND RAT ERYTHROCYTE GHOSTS [J].

BRUCKDORFER, KR ;

GREEN, C .

BIOCHEMICAL JOURNAL, 1967, 104 (01) :270-+

[10] REGULATION OF CHOLESTEROL METABOLISM .1. [J].

DIETSCHY, JM ;

WILSON, JD .

NEW ENGLAND JOURNAL OF MEDICINE, 1970, 282 (20) :1128-+

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