AMNIOTIC-FLUID REACTIVITY DETECTED BY SOMATOMEDIN C RADIORECEPTOR ASSAY - CORRELATION WITH GROWTH-HORMONE, PROLACTIN AND FETAL RENAL MATURATION

被引：57

作者：

CHOCHINOV, RH

KETUPANYA, A

MARIZ, IK

UNDERWOOD, LE

DAUGHADAY, WH

机构：

[1] WASHINGTON UNIV, SCH MED, DEPT OBSTET & GYNECOL, PERINATAL UNIT, ST LOUIS, MO 63110 USA

[2] UNIV N CAROLINA, DEPT PEDIAT, CHAPEL HILL, NC 27514 USA

[3] WASHINGTON UNIV, SCH MED, DEPT MED, DIV METAB, ST LOUIS, MO 63110 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1976年 / 42卷 / 05期

关键词：

D O I：

10.1210/jcem-42-5-983

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Amniotic fluid was assayed by a radioreceptor assay utilizing 125I-somatomedin C and placental membranes. Growth hormone and prolactin levels were measured by radioimmunoassay at different gestational ages (8-41 wk). Somatomedin receptor activity, growth hormone and prolactin reached high levels during early gestation (8-26 wk) displaying different patterns of appearance which reflect fetal serum levels of these hormones. After 26 wk gestation all these hormones decreased in concentration. This decrease showed a strong correlation with [human] fetal renal maturation as measured by amniotic fluid creatinine levels.

引用

页码：983 / 986

页数：4

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