IDENTIFICATION OF A POINT MUTATION IN THE ADENOSINE-DEAMINASE GENE RESPONSIBLE FOR IMMUNODEFICIENCY

被引：79

作者：

BONTHRON, DT

MARKHAM, AF

GINSBURG, D

ORKIN, SH

机构：

[1] CHILDRENS HOSP MED CTR,DIV HEMATOL ONCOL,320 LONGWOOD AVE,BOSTON,MA 02115

[2] BRIGHAM & WOMENS HOSP,DIV HEMATOL ONCOL,BOSTON,MA 02115

[3] ICI LTD,DIV PHARMACEUT,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1985年 / 76卷 / 02期

关键词：

D O I：

10.1172/JCI112050

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：894 / 897

页数：4

共 24 条

[11]

MANIATIS T, 1982, MOL CLONING LABORATO

[12] SOLID-PHASE PHOSPHOTRIESTER SYNTHESIS OF LARGE OLIGODEOXYRIBONUCLEOTIDES ON A POLYAMIDE SUPPORT [J].

MARKHAM, AF ;

EDGE, MD ;

ATKINSON, TC ;

GREENE, AR ;

HEATHCLIFFE, GR ;

NEWTON, CR ;

SCANLON, D .

NUCLEIC ACIDS RESEARCH, 1980, 8 (22) :5193-5205

[13] BIOCHEMISTRY OF DISEASES OF IMMUNODEVELOPMENT [J].

MARTIN, DW ;

GELFAND, EW .

ANNUAL REVIEW OF BIOCHEMISTRY, 1981, 50 :845-877

[14]

MESSING J, 1983, METHOD ENZYMOL, V101, P20

[15] HIGH-EFFICIENCY CLONING OF FULL-LENGTH CDNA [J].

OKAYAMA, H ;

BERG, P .

MOLECULAR AND CELLULAR BIOLOGY, 1982, 2 (02) :161-170

[16] TRANSIENT EXPRESSION OF HUMAN ADENOSINE-DEAMINASE CDNAS - IDENTIFICATION OF A NONFUNCTIONAL CLONE RESULTING FROM A SINGLE AMINO-ACID SUBSTITUTION [J].

ORKIN, SH ;

GOFF, SC ;

KELLEY, WN ;

DADDONA, PE .

MOLECULAR AND CELLULAR BIOLOGY, 1985, 5 (04) :762-767

[17]

ORKIN SH, 1983, J BIOL CHEM, V258, P2753

[18] DNA SEQUENCING WITH CHAIN-TERMINATING INHIBITORS [J].

SANGER, F ;

NICKLEN, S ;

COULSON, AR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5463-5467

[19] DETECTION OF SPECIFIC SEQUENCES AMONG DNA FRAGMENTS SEPARATED BY GEL-ELECTROPHORESIS [J].

SOUTHERN, EM .

JOURNAL OF MOLECULAR BIOLOGY, 1975, 98 (03) :503-+

[20]

UBERTI J, 1983, J IMMUNOL, V130, P2866

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