The role of immune responses in bone loss during periodontal disease

被引：114

作者：

Baker, PJ ^{[1
]}

机构：

[1] Bates Coll, Dept Biol, Lewiston, ME 04240 USA

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 10期

关键词：

periodontal disease; bone remodeling; interleukin-1; interleukin-6; tumor necrosis factor alpha; RANK-ligand;

D O I：

10.1016/S1286-4579(00)01272-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A network of cytokines and other soluble mediators unites the immune system and bone; bacterial infections induce immune responses which may perturb this network. Periodontal diseases are Gram-negative infections resulting in bone loss in the jaw. Evidence is presented that immune responses to these infections produces net resorption of bone. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

引用

页码：1181 / 1192

页数：12

共 91 条

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[2]

Assuma R, 1998, J IMMUNOL, V160, P403

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