Characterisation of an avian influenza A virus isolated from a human - is an intermediate host necessary for the emergence of pandemic influenza viruses?

被引：91

作者：

Banks, J ^{[1
]}

Speidel, E ^{[1
]}

Alexander, DJ ^{[1
]}

机构：

[1] MAFF, Cent Vet Lab, Weybridge KT15 3NB, Surrey, England

来源：

ARCHIVES OF VIROLOGY | 1998年 / 143卷 / 04期

关键词：

D O I：

10.1007/s007050050329

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The partial sequencing of the internal and the neuraminidase genes of isolate 268/96 obtained from a woman with conjunctivitis showed all seven to have closest homology with avian influenza viruses. The entire nucleotide sequence of the haemagglutinin gene of 268/96 had close, 98.2%, homology with an H7N7 virus isolated from turkeys in Ireland in 1995. This appears to be the first reported case of isolation of an influenza A virus from a human being infected as a result of direct natural transmission of an avian influenza virus from birds.

引用

页码：781 / 787

页数：7

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