Recent pharmacological studies on natural products in China

被引:103
作者
Zhu, XZ [1 ]
Li, XY [1 ]
Liu, J [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
关键词
natural product; huperzine A; s-(-)-3-n-butylphthalide; (-)-clausenamide; Ginkgo biloba extract;
D O I
10.1016/j.ejphar.2004.07.027
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Natural products have been used as medicinal agents for many years. In addition, these compounds have also served as the starting points for semisynthetic analogs with improved properties. This review focuses on recent advances in the pharmacological studies on natural products mainly performed and published in China. Emphasis will be placed on those compounds that show the greatest promise clinically such as huperzine A (9-amino-13-ethylidene-11-methyl-4-azatricyclo[7.3.1.0(3.8)]trideca-3(8),6,11-trien-5-one), s-(-)-3-n-butylphthalide (s-(-)-3-butyl-1(3H)-isobenzofuranone), (-)-clausenamide (3-hydroxy-4-phenyl-5alpha-hydroxybenzyl-N-methyl-gamma-lactam) and Ginkgo biloba extract and its active components. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:221 / 230
页数:10
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