Progress toward understanding the molecular mechanisms of neurotrophic factor signalling

被引：17

作者：

Gunn-Moore, FJ ^{[1
]}

Tavaré, JM ^{[1
]}

机构：

[1] Univ Bristol, Sch Med Sci, Dept Biochem, Bristol BS8 1TD, Avon, England

来源：

CELLULAR SIGNALLING | 1998年 / 10卷 / 03期

基金：

英国惠康基金;

关键词：

primary neurons; neurotrophic factors; signalling; tyrosine phosphorylation; protein kinases;

D O I：

10.1016/S0898-6568(97)00114-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Understanding the mechanism of action of the neurotrophic factors is central to unravelling of the mysteries of some of the neurodegenerative disorders. In this review we will discuss recent advances in our understanding of neurotrophic factor signalling in primary cultured neurons, in particular those from the superior cervical and dorsal root ganglia, as well as cerebellar granule cells, cortical neurons and oligodendrocytes. (C) 1998 Elsevier Science Inc.

引用

页码：151 / 157

页数：7