Current management of bloodstream infections

被引:29
作者
Rodriguez-Bano, Jesus [1 ,2 ]
de Cueto, Marina [1 ,3 ]
Retamar, Pilar [1 ]
Galvez-Acebal, Juan [1 ,2 ]
机构
[1] Hosp Univ Virgen Macarena, Unidad Clin Enfermedades Infecciosas & Microbiol, Seville 41009, Spain
[2] Univ Seville, Dept Med, Seville, Spain
[3] Univ Seville, Dept Microbiol, Seville, Spain
关键词
antimicrobial resistance; bacteremia; bloodstream infections; community-acquired infections; nosocomial infections; sepsis; COAGULASE-NEGATIVE STAPHYLOCOCCI; POLYMERASE-CHAIN-REACTION; BETA-LACTAMASE PRODUCTION; KLEBSIELLA-PNEUMONIAE; ANTIMICROBIAL THERAPY; MOLECULAR EPIDEMIOLOGY; MULTIDRUG-RESISTANT; RISK-FACTORS; ANTIBIOTIC-RESISTANCE; CLINICAL-FEATURES;
D O I
10.1586/ERI.10.49
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Bloodstream infection (BSI) is a frequent complication of invasive infections. The presence of bacteremia has therapeutic and prognostic implications. Here we review recent changes in the epidemiology, diagnosis and treatment of BSI (excluding candidemia). The evidence of the impact of healthcare-association in many community-onset episodes and the increase in drug-resistant pathogens causing BSI in the community and hospitals is reviewed. The emergence of molecular methods as an alternative tool for the diagnosis of BSI and novel aspects of clinical management, particularly of some multidrug-resistant organisms. Several quality indicators related to the diagnosis and management of bacteremia in hospitals are proposed.
引用
收藏
页码:815 / 829
页数:15
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