Conserved noncoding sequences are reliable guides to regulatory elements

被引:338
作者
Hardison, RC [1 ]
机构
[1] Penn State Univ, Dept Biochem & Mol Biol, University Pk, PA 16802 USA
关键词
D O I
10.1016/S0168-9525(00)02081-3
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci.
引用
收藏
页码:369 / 372
页数:4
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