Electron tomography: towards visualizing the molecular organization of the cytoplasm

被引:169
作者
Baumeister, W [1 ]
机构
[1] Max Planck Inst Biochem, Dept Biol Struct, D-82152 Martinsried, Germany
关键词
D O I
10.1016/S0959-440X(02)00378-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Electron tomography of thin sections of plastic-em bedded biological material provides valuable insights into the organellar organization of cells, With the advent of automated data-acquisition procedures, it has become possible to study radiation-sensitive specimens, such as frozen-hydrated organelles and whole cells. This opens up exciting perspectives for visualizing the molecular organization of the cytoplasm.
引用
收藏
页码:679 / 684
页数:6
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