Mitochondrial control of cell death

被引：2736

作者：

Kroemer, G

Reed, JC

机构：

[1] Inst Gustave Roussy, CNRS, ULR 1599, F-94805 Villejuif, France

[2] Burnham Inst, La Jolla, CA 92037 USA

来源：

NATURE MEDICINE | 2000年 / 6卷 / 05期

关键词：

D O I：

10.1038/74994

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In many instances, permeabilization of mitochondrial membranes is a rate-limiting step of apoptotic or necrotic cell demise. This has important consequences for the pathophysiology of cell death, as well as for its pharmacological control.

引用

页码：513 / 519

页数：7

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