RNA interference: antiviral defense and genetic tool

被引:104
作者
Cullen, BR
机构
[1] Duke Univ, Med Ctr, Howard Hughes Med Inst, Durham, NC 27710 USA
[2] Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27710 USA
关键词
D O I
10.1038/ni0702-597
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Higher eukaryotes can mount antiviral immune responses induced by dsRNA. This process, called RNA interference, is sequence specific and can therefore be used to target gene expression.
引用
收藏
页码:597 / 599
页数:3
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