Interleukin-1β and the Autoinflammatory Diseases

被引：170

作者：

Dinarello, Charles A. ^{[1
]}

机构：

[1] Univ Colorado Denver, Div Infect Dis, Aurora, CO USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2009年 / 360卷 / 23期

关键词：

RECEPTOR ANTAGONIST; GENE; IL-1-BETA; ANAKINRA; PROTEIN; IL-1; OSTEOARTHRITIS; PATHOGENESIS; ASSOCIATION; INHIBITION;

D O I：

10.1056/NEJMe0811014

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2467 / 2470

页数：4

共 23 条

[11] Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome [J].

Hoffman, HM ;

Mueller, JL ;

Broide, DH ;

Wanderer, AA ;

Kolodner, RD .

NATURE GENETICS, 2001, 29 (03) :301-305

[12] Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome [J].

Lachmann, Helen J. ;

Kone-Paut, Isabelle ;

Kuemmerle-Deschner, Jasmin B. ;

Leslie, Kieron S. ;

Hachulla, Eric ;

Quartier, Pierre ;

Gitton, Xavier ;

Widmer, Albert ;

Patel, Neha ;

Hawkins, Philip N. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (23) :2416-2425

[13] Interleukin-1-receptor antagonist in type 2 diabetes mellitus [J].

Larsen, Claus M. ;

Faulenbach, Mirjam ;

Vaag, Allan ;

Volund, Aage ;

Ehses, Jan A. ;

Seifert, Burkhardt ;

Mandrup-Poulsen, Thomas ;

Donath, Marc Y. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (15) :1517-1526

[14] Interleukin-1 receptor antagonist gene polymorphisms are associated with disease severity in Black South Africans with rheumatoid arthritis [J].

Lubbe, Steven ;

Tikly, Mohammed ;

van der Merwe, Lize ;

Hodkinson, Bridget ;

Ramsay, Michele .

JOINT BONE SPINE, 2008, 75 (04) :422-425

[15] Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets [J].

Maedler, K ;

Sergeev, P ;

Ris, F ;

Oberholzer, J ;

Joller-Jemelka, HI ;

Spinas, GA ;

Kaiser, N ;

Halban, PA ;

Donath, MY .

JOURNAL OF CLINICAL INVESTIGATION, 2002, 110 (06) :851-860

[16] MONOKINE ANTAGONISM IS REDUCED IN PATIENTS WITH IDDM [J].

MANDRUPPOULSEN, T ;

POCIOT, F ;

MOLVIG, J ;

SHAPIRO, L ;

NILSSON, P ;

EMDAL, T ;

RODER, M ;

KJEMS, LL ;

DINARELLO, CA ;

NERUP, J .

DIABETES, 1994, 43 (10) :1242-1247

[17] Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip [J].

Meulenbelt, I ;

Seymour, AB ;

Nieuwland, M ;

Huizinga, TWJ ;

van Duijn, CM ;

Slagboom, PE .

ARTHRITIS AND RHEUMATISM, 2004, 50 (04) :1179-1186

[18] Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade [J].

Pascual, V ;

Allantaz, F ;

Arce, E ;

Punaro, M ;

Banchereau, J .

JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 201 (09) :1479-1486

[19] Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels [J].

Rafiq, S. ;

Stevens, K. ;

Hurst, A. J. ;

Murray, A. ;

Henley, W. ;

Weedon, M. N. ;

Bandinelli, S. ;

Corsi, A. M. ;

Guralnik, J. M. ;

Ferruci, L. ;

Melzer, D. ;

Frayling, T. M. .

GENES AND IMMUNITY, 2007, 8 (04) :344-351

[20] BRIEF REPORT An Autoinflammatory Disease Due to Homozygous Deletion of the IL1RN Locus [J].

Reddy, Sreelatha ;

Jia, Shuang ;

Geoffrey, Rhonda ;

Lorier, Rachel ;

Suchi, Mariko ;

Broeckel, Ulrich ;

Hessner, Martin J. ;

Verbsky, James .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (23) :2438-2444

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