All in the family:: IL-27 suppression of TH-17 cells

被引：42

作者：

Colgan, John ^{[1
]}

Rothman, Paul ^{[1
]}

机构：

[1] Univ Iowa, Dept Internal Med, Iowa City, IA 52242 USA

来源：

NATURE IMMUNOLOGY | 2006年 / 7卷 / 09期

关键词：

D O I：

10.1038/ni0906-899

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Interleukin 17 (IL-17)-producing T cells are associated with inflammatory conditions. Two studies now show that IL-27, an IL-12 family member with both pro- and anti-inflammatory properties, potently suppresses the development of IL-17-producing T cells.

引用

页码：899 / 901

页数：3

共 13 条

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