Maternal nutrition, fetal nutrition, and disease in later life

被引:540
作者
Barker, DJP
机构
[1] MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton
关键词
maternal nutrition; fetal nutrition; birthweight fetus; coronary heart disease; non-insulin-dependent diabetes mellitus;
D O I
10.1016/S0899-9007(97)00193-7
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Recent findings suggest that many human fetuses have to adapt to a limited supply of nutrients and in doing so they permanently change their physiology and metabolism. These ''programmed'' changes may be the origins of a number of diseases in later life, including coronary heart disease and the related disorders stroke, diabetes, and hypertension. (C) Elsevier Science Inc. 1997.
引用
收藏
页码:807 / 813
页数:7
相关论文
共 63 条
[51]  
SNOW MHL, 1989, FETAL GROWTH, P1
[52]   Fetal growth and coronary heart disease in South India [J].
Stein, CE ;
Fall, CHD ;
Kumaran, K ;
Osmond, C ;
Cox, V ;
Barker, DJP .
LANCET, 1996, 348 (9037) :1269-1273
[53]   PERSISTENT IMPAIRMENT OF INSULIN SECRETORY RESPONSE TO GLUCOSE IN ADULT-RATS AFTER LIMITED PERIOD OF PROTEIN-CALORIE MALNUTRITION EARLY IN LIFE [J].
SWENNE, I ;
CRACE, CJ ;
MILNER, RDG .
DIABETES, 1987, 36 (04) :454-458
[54]  
TAYLOR DJ, 1995, DIABETOLOGIA, V73, P363
[55]   ISCHEMIC-HEART-DISEASE AND LOW-BIRTH-WEIGHT - A TEST OF THE FETAL-ORIGINS HYPOTHESIS FROM THE SWEDISH-TWIN-REGISTRY [J].
VAGERO, D ;
LEON, D .
LANCET, 1994, 343 (8892) :260-263
[56]   BIRTH-WEIGHT AND ADULT HEALTH OUTCOMES IN A BIETHNIC POPULATION IN THE USA [J].
VALDEZ, R ;
ATHENS, MA ;
THOMPSON, GH ;
BRADSHAW, BS ;
STERN, MP .
DIABETOLOGIA, 1994, 37 (06) :624-631
[57]  
VIJAYAKUMAR M, 1995, BRIT HEART J, V73, P363
[58]  
VILLAR J, 1984, PEDIATRICS, V74, P783
[59]   The maternal effects on growth and conformation in Shire horse-Shetland pony crosses [J].
Walton, A ;
Hammond, J .
PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1938, 125 (840) :311-335
[60]   RELATION BETWEEN MATERNAL HEMOGLOBIN AND PLACENTAL HORMONE CONCENTRATIONS IN EARLY-PREGNANCY [J].
WHEELER, T ;
SOLLERO, C ;
ALDERMAN, S ;
LANDEN, J ;
ANTHONY, F ;
OSMOND, C .
LANCET, 1994, 343 (8896) :511-513