Rho: Theme and variations

被引：267

作者：

Ridley, AJ ^{[1
]}

机构：

[1] UNIV LONDON UNIV COLL,DEPT BIOCHEM & MOL BIOL,LONDON WC1E 6BT,ENGLAND

来源：

CURRENT BIOLOGY | 1996年 / 6卷 / 10期

关键词：

D O I：

10.1016/S0960-9822(02)70711-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In addition to their roles in organizing the actin cytoskeleton, members of the Rho family of GTP-binding proteins have recently been implicated in a plethora of other functions, including the activation of kinase cascades and transcription factors, and the control of endocytosis and secretion. Alongside this expansion in proposed functions has been the identification of multiple target proteins that interact directly with Rho, Rac or Cdc42. Molecular connections are now being made along the signalling pathways activated by members of the Rho family. (C) Current Biology Ltd ISSN 0960-9822

引用

页码：1256 / 1264

页数：9

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