Regulation of protein phosphatase-1

被引：157

作者：

Aggen, JB

Nairn, AC

Chamberlin, R ^{[1
]}

机构：

[1] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA

[2] Rockefeller Univ, Mol & Cellular Neurosci Lab, New York, NY 10021 USA

来源：

CHEMISTRY & BIOLOGY | 2000年 / 7卷 / 01期

关键词：

D O I：

10.1016/S1074-5521(00)00069-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Reversible protein phosphorylation is a major regulatory mechanism of intracellular signal transduction. Protein phosphatase 1 (PP1) is one of four major types of serine-threonine phosphatases mediating signaling pathways, but the means by which its activity is modulated has only recently begun to come into focus.

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收藏

页码：R13 / R23

页数：11

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