Scanning thermoacoustic tomography in biological tissue

被引：128

作者：

Ku, G ^{[1
]}

Wang, LHV ^{[1
]}

机构：

[1] Texas A&M Univ, Opt Imaging Lab, Biomed Engn Program, College Stn, TX 77843 USA

来源：

MEDICAL PHYSICS | 2000年 / 27卷 / 05期

关键词：

microwave; ultrasonics; thermoacoustics; photoacoustics; tomography;

D O I：

10.1118/1.598984

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Microwave-induced thermoacoustic tomography was explored to image biological tissue. Short microwave pulses irradiated tissue to generate acoustic waves by thermoelastic expansion. The microwave-induced thermoacoustic waves were detected with a focused ultrasonic transducer. Each time-domain signal from the ultrasonic transducer represented a one-dimensional image along the acoustic axis of the ultrasonic transducer similar to an ultrasonic A-scan. Scanning the system perpendicularly to the acoustic axis of the ultrasonic transducer would generate multi-dimensional images. Two-dimensional tomographic images of biological tissue were obtained with 3-GHz microwaves. The axial and lateral resolutions were characterized. The time-domain piezo-electric signal from the ultrasonic transducer in response to the thermoacoustic signal was simulated theoretically, and the theoretical result agreed with the experimental result very well. (C) 2000 American Association of Physicists in Medicine. [S0094-2405(00)03105-9].

引用

页码：1195 / 1202

页数：8

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