Epigenetic consequences of nucleosome dynamics

被引：100

作者：

Ahmad, K ^{[1
]}

Henikoff, S ^{[1
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA

来源：

CELL | 2002年 / 111卷 / 03期

关键词：

D O I：

10.1016/S0092-8674(02)01081-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Current models for epigenetic gene silencing envision a static relationship between histone modifications and transcription. However, evidence for nucleosome mobility and replacement favors a dynamic model that may explain phenomena ranging from variegation to the neural restriction of Rett syndrome.

引用

收藏

页码：281 / 284

页数：4

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