Fibulins: physiological and disease perspectives

被引：255

作者：

Argraves, WS

Greene, LM

Cooley, MA

Gallagher, WM

机构：

[1] Med Univ S Carolina, Dept Cell Biol, Charleston, SC 29425 USA

[2] Univ Coll Dublin, Conway Inst Biomol & Biomed Res, Dept Pharmacol, Dublin 4, Ireland

来源：

EMBO REPORTS | 2003年 / 4卷 / 12期

关键词：

D O I：

10.1038/sj.embor.7400033

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The fibulins are a family of proteins that are associated with basement membranes and elastic extracellular matrix fibres. This review summarizes findings from studies of animal models of fibulin deficiency, human fibulin gene mutations, human tumours and injury models that have advanced our understanding of the normal and pathological roles of members of this formerly obscure family.

引用

收藏

页码：1127 / 1131

页数：5

相关论文

共 62 条

[1] Identification of a novel set of genes regulated by a unique liver X receptor-α-mediated transcription mechanism [J].

Anderson, LM ;

Choe, SE ;

Yukhananov, RY ;

Hopfner, RL ;

Church, GM ;

Pratt, RE ;

Dzau, VJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (17) :15252-15260

[2]

Arai M, 2001, JPN J THROMB HEMOST, V12, P126

[3] FIBULIN IS AN EXTRACELLULAR-MATRIX AND PLASMA GLYCOPROTEIN WITH REPEATED DOMAIN-STRUCTURE [J].

ARGRAVES, WS ;

TRAN, H ;

BURGESS, WH ;

DICKERSON, K .

JOURNAL OF CELL BIOLOGY, 1990, 111 (06) :3155-3164

[4] FIBULIN, A NOVEL PROTEIN THAT INTERACTS WITH THE FIBRONECTIN RECEPTOR-BETA SUBUNIT CYTOPLASMIC DOMAIN [J].

ARGRAVES, WS ;

DICKERSON, K ;

BURGESS, WH ;

RUOSLAHTI, E .

CELL, 1989, 58 (04) :623-629

[5]

Bell SE, 2001, J CELL SCI, V114, P2755

[6]

Bouchey D, 1996, ANAT RECORD, V244, P540

[7] Structural and functional characterization of the human and mouse fibulin-1 gene promoters: role of Sp1 and Sp3 [J].

Castoldi, M ;

Chu, ML .

BIOCHEMICAL JOURNAL, 2002, 362 :41-50

[8] Mutation of the gene encoding fibrillin-2 results in syndactyly in mice [J].

Chaudhry, SS ;

Gazzard, J ;

Baldock, C ;

Dixon, J ;

Rock, MJ ;

Skinner, GC ;

Steel, KP ;

Kielty, CM ;

Dixon, MJ .

HUMAN MOLECULAR GENETICS, 2001, 10 (08) :835-843

[9] Estrogens increase the expression of fibulin-1, an extracellular matrix protein secreted by human ovarian cancer cells [J].

Clinton, GM ;

Rougeot, C ;

Derancourt, J ;

Roger, P ;

Defrenne, A ;

Godyna, S ;

Argraves, WS ;

Rochefort, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (01) :316-320

[10]

CREIGHTON C, 2003, N SILICO BIOL, V3, P26

← 1 2 3 4 5 6 7 →