Neuroinflammatory responses in the Alzheimer's disease brain promote the oxidative post-translational modification of amyloid deposits

被引：22

作者：

Atwood, CS ^{[1
]}

Huang, XD ^{[1
]}

Moir, RD ^{[1
]}

Smith, MA ^{[1
]}

Tanzi, RE ^{[1
]}

Roher, AE ^{[1
]}

Bush, AI ^{[1
]}

Perry, G ^{[1
]}

机构：

[1] Case Western Reserve Univ, Inst Pathol, Cleveland, OH 44106 USA

来源：

ALZHEIMER'S DISEASE: ADVANCES IN ETIOLOGY, PATHOGENESIS AND THERAPEUTICS | 2001年

关键词：

D O I：

10.1002/0470846453.ch32

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：341 / 361

页数：21

共 175 条

[61] SENILE PLAQUES STIMULATE MICROGLIA TO RELEASE A NEUROTOXIN FOUND IN ALZHEIMER BRAIN [J].

GIULIAN, D ;

HAVERKAMP, LJ ;

LI, J ;

KARSHIN, WL ;

YU, J ;

TOM, D ;

LI, X ;

KIRKPATRICK, JB .

NEUROCHEMISTRY INTERNATIONAL, 1995, 27 (01) :119-137

[62] ALZHEIMERS-DISEASE - INITIAL REPORT OF THE PURIFICATION AND CHARACTERIZATION OF A NOVEL CEREBROVASCULAR AMYLOID PROTEIN [J].

GLENNER, GG ;

WONG, CW .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (03) :885-890

[63] INTERLEUKIN-1 REGULATES SYNTHESIS OF AMYLOID BETA-PROTEIN PRECURSOR MESSENGER-RNA IN HUMAN-ENDOTHELIAL CELLS [J].

GOLDGABER, D ;

HARRIS, HW ;

HLA, T ;

MACIAG, T ;

DONNELLY, RJ ;

JACOBSEN, JS ;

VITEK, MP ;

GAJDUSEK, DC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (19) :7606-7610

[64]

GRIFFIN WST, 1995, J NEUROPATH EXP NEUR, V54, P276

[65] INCREASED AMYLOID PROTEIN-PRECURSOR AND APOLIPOPROTEIN-E IMMUNOREACTIVITY IN THE SELECTIVELY VULNERABLE HIPPOCAMPUS FOLLOWING TRANSIENT FOREBRAIN ISCHEMIA IN GERBILS [J].

HALL, ED ;

OOSTVEEN, JA ;

DUNN, E ;

CARTER, DB .

EXPERIMENTAL NEUROLOGY, 1995, 135 (01) :17-27

[66] Molecular chlorine generated by the myeloperoxidase hydrogen peroxide chloride system of phagocytes converts low density lipoprotein cholesterol into a family of chlorinated sterols [J].

Hazen, SL ;

Hsu, FF ;

Duffin, K ;

Heinecke, JW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (38) :23080-23088

[67] 3-chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima [J].

Hazen, SL ;

Heinecke, JW .

JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (09) :2075-2081

[68]

Hensley K, 1998, J NEUROSCI, V18, P8126

[69] ALTERED LEVELS OF AMYLOID PROTEIN-PRECURSOR TRANSCRIPTS IN THE BASAL FOREBRAIN OF BEHAVIORALLY IMPAIRED AGED RATS [J].

HIGGINS, GA ;

OYLER, GA ;

NEVE, RL ;

CHEN, KS ;

GAGE, FH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (08) :3032-3036

[70] The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction [J].

Huang, XD ;

Atwood, CS ;

Hartshorn, MA ;

Multhaup, G ;

Goldstein, LE ;

Scarpa, RC ;

Cuajungco, MP ;

Gray, DN ;

Lim, J ;

Moir, RD ;

Tanzi, RE ;

Bush, AI .

BIOCHEMISTRY, 1999, 38 (24) :7609-7616

← 2 3 4 5 6 7 8 9 10 11 →