Functional annotation of a full-length mouse cDNA collection

被引：527

作者：

Kawai, J

Shinagawa, A

Shibata, K

Yoshino, M

Itoh, M

Ishii, Y

Arakawa, T

Hara, A

Fukunishi, Y

Konno, H

Adachi, J

Fukuda, S

Aizawa, K

Izawa, M

Nishi, K

Kiyosawa, H

Kondo, S

Yamanaka, I

Saito, T

Okazaki, Y

Gojobori, T

Bono, H

Kasukawa, T

Saito, R

Kadota, K

Matsuda, H

Ashburner, M

Batalov, S

Casavant, T

Fleischmann, W

Gaasterland, T

Gissi, C

King, B

Kochiwa, H

Kuehl, P

Lewis, S

Matsuo, Y

Nikaido, I

Pesole, G

Quackenbush, J

Schriml, LM

Staubli, F

Suzuki, R

Tomita, M

Wagner, L

Washio, T

Sakai, K

Okido, T

Furuno, M

Aono, H

机构：

[1] Yokohama Inst, RIKEN Genom Sci Ctr, Lab Genome Explorat, Res Grp,Tsurumi Ku, Kanagawa 2300045, Japan

[2] JST, CREST, Tsukuba, Ibaraki 3050074, Japan

[3] Natl Inst Genet, Ctr Informat Biol, Shizuoka 4118540, Japan

[4] NTT Software Corp, Naka Ku, Kanagawa 2318554, Japan

[5] Osaka Univ, Osaka 5608531, Japan

[6] European Bioinformat Inst, European Mol Biol Lab, Cambridge CB10 1SD, England

[7] Novartis Res Fdn, Genom Inst, San Diego, CA 92121 USA

[8] Univ Iowa, Coordinated Lab Computat Genom, Iowa City, IA 52242 USA

[9] Rockefeller Univ, New York, NY 10021 USA

[10] Univ Milan, Dipartimento Fisiol & Biochim Gen, I-20133 Milan, Italy

[11] Jackson Lab, Bar Harbor, ME 04609 USA

[12] Keio Univ, Fac Environm Informat, Lab Bioinformat, Kanagawa 2520816, Japan

[13] Univ Maryland, Dept Mol & Cell Biol, Baltimore, MD 20201 USA

[14] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

[15] Yokohama Inst, RIKEN Genom Sci Ctr, Bioinformat Grp, Computat Proteom Team,Tsurumi Ku, Kanagawa 2300045, Japan

[16] Tokai Univ, Grad Sch Marine Sci & Technol, Shizuoka 4248610, Japan

[17] Inst Genom Res, Rockville, MD 20850 USA

[18] NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20894 USA

[19] LION Biosci AG, D-69120 Heidelberg, Germany

[20] Stanford Univ, Sch Med, Beckman Ctr B271A, Stanford, CA 94305 USA

[21] Lawrence Berkeley Lab, Berkeley, CA 94710 USA

[22] Univ Iowa, Dept Pediat, Iowa City, IA 52242 USA

[23] NIMH, Genet Lab, NHGRI, NIH, Bethesda, MD 20892 USA

[24] Univ Tokyo, Grad Sch Med, Bunkyo Ku, Tokyo 1138655, Japan

[25] Ist Tumori Milano, I-20133 Milan, Italy

[26] Harvard Univ, Sch Med, Dept Neurobiol, Boston, MA 02115 USA

[27] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia

[28] Univ Cambridge, Addenbrookes Hosp, Wellcome Trust Ctr Mol Mechanisms Dis, Dept Med Genet, Cambridge CB2 2XY, England

[29] LNCIB, I-34012 Trieste, Italy

[30] Univ Penn, Ctr Bioinformat, Computat & Bioinformat Lab, Philadelphia, PA 19104 USA

[31] Univ Buffalo, Roswell Pk Canc Inst, Amherst, NY 14226 USA

[32] Stanford Univ, Dept Genet, Beckman Ctr B281, Stanford, CA 94305 USA

[33] RIKEN, Brain Sci Inst, Wako, Saitama 3510198, Japan

[34] Natl Canc Res Inst, Chuo Ku, Tokyo 1040045, Japan

[35] Yokohama Inst, RIKEN Genom Sci Ctr, Bioinformat Grp, Computat Genom Team,Tsurumi Ku, Kanagawa 2300045, Japan

[36] Osaka Med Ctr Canc, Higashinari Ku, Osaka 5378511, Japan

[37] Univ Calif San Diego, Sch Med, Dept Pediat, La Jolla, CA 92093 USA

[38] MIT, Ctr Learning & Memory, Cambridge, MA 02139 USA

[39] MIT, MIT CCR, Cambridge, MA 02139 USA

[40] Sanger Ctr, Hinxton CB10 1SA, Cambs, England

[41] Univ Tsukuba, Tsukuba, Ibaraki 3058577, Japan

来源：

NATURE | 2001年 / 409卷 / 6821期

关键词：

D O I：

10.1038/35055500

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The RIKEN Mouse Gene Encyclopaedia Project, a systematic approach to determining the full coding potential of the mouse genome, involves collection and sequencing of full-length complementary DNAs and physical mapping of the corresponding genes to the mouse genome. We organized an international functional annotation meeting (FANTOM) to annotate the first 21,076 cDNAs to be analysed in this project. Here we describe the first RIKEN clone collection, which is one of the largest described for any organism. Analysis of these cDNAs extends known gene families and identifies new ones.

引用

页码：685 / 690

页数：6

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