Finding the genes in genomic DNA

被引：425

作者：

Burge, CB

Karlin, S

机构：

[1] Stanford Univ, Dept Math, Stanford, CA 94305 USA

[2] MIT, Ctr Canc Res, Cambridge, MA 02139 USA

[3] MIT, Dept Biol, Cambridge, MA 02139 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1998年 / 8卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(98)80069-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Genome sequencing efforts will soon generate hundreds of millions of bases of human genomic DNA containing thousands of novel genes. In the past year, the accuracy of computational gene-finding methods has improved significantly to the point where a reasonable approximation of the gene structures within an extended genomic region can often be predicted in advance of more detailed experimental studies.

引用

页码：346 / 354

页数：9

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