Robbins, empirical Bayes and microarrays

被引:89
作者
Efron, B [1 ]
机构
[1] Stanford Univ, Dept Stat, Stanford, CA 94305 USA
关键词
false discovery rate; missing species; q-value; Stein estimation; simultaneous inference;
D O I
10.1214/aos/1051027871
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Empirical Bayes was Herbert Robbins' most influential contribution to statistical theory. It is also an idea of great practical potential. That potential is realized in the analysis of microarrays, a new biogenetic technology for the simultaneous measurement of thousands of gene expression levels.
引用
收藏
页码:366 / 378
页数:13
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